Do not install .NET Framework 4.6.1 on Exchange servers
A note has been published on the Exchange Team Blog stating that .NET Framework 4.6.1 should not be installed on Exchange servers at the moment: http://blogs.technet.com/b/exchange/archive/2016/02/10/on-net-framework-4-6-1-and-exchange-compatibility.aspx In conjunction with .NET Framework 4.6.1, the databases may also be taken offline. The only remedy at the moment is to uninstall .NET Framework 4.6.1: https://support.microsoft.com/en-us/kb/3095369 Currently ... Read more